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- Projects
- P1 (Stehle) - Retargeting and Inhibition of Glycan-Binding Polyomaviruses
- P2 (Blaum) - Differential Roles of Two Types of Glycans for Cell Attachment and Entry of Merkel Cell Polyomavirus
- P3 (Hansman) - Binding Adaptability of Caliciviruses to Histo-Blood Group Antigens
- P4 (Schelhaas) - The Functional Role of Glycosaminoglycan-Papillomavirus Interactions: Inhibition versus Activation
- P5 (Taube) - The Role of Glycan-Binding in Norovirus Infection - A Biological Approach
- P6 (Peters) - Design of Carbohydrate-Inspired Ligands to Modulate Entry of Murine Noroviruses into Host Cells
- P7 (Hartmann) - Heteromultivalent Glycomacromolecules as Sensors and Inhibitors of Viral Interactions
- P8 (Uetrecht) - Structural Impact of Glycan Binding on Viral Particles
- P9 (Ewers) - Valency and Geometry of Multivalent Glycolipid Binding as Cellular Targeting Mechanism in Viral Infection
- Publications
- Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides
- STD NMR Titrations Reveal Complex Multistep-Binding of L-Fucose to Norovirus Particles.
- Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides.
- A rigid lanthanide binding tag to aid NMR studies of a 70 kDa homodimeric coat protein of human norovirus.
- Production of Human Norovirus Protruding Domains in E. coli for X-ray Crystallography.
- Structural Constraints on Human Norovirus Binding to Histo-Blood Group Antigens.
- Development of a Nanobody-Based Lateral Flow Immunoassay for Detection of Human Norovirus.
- Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures.
- Human Norovirus Evolution in a Chronically Infected Host.
- Prevalence of human norovirus and Clostridium difficile coinfections in adult hospitalized patients.
- Viral Genome Tethering to Host Cell Chromatin: Cause and Consequences.
- Multivalent display of minimal Clostridium difficile glycan epitopes mimics antigenic properties of larger glycans.
- Native and engineered tropism of vectors derived from a rare species D adenovirus serotype 43.
- Sequence-Controlled Glycopolymers via Step-Growth Polymerization of Precision Glycomacromolecules for Lectin Receptor Clustering.
- Structural Insights into Reovirus σ1 Interactions with Two Neutralizing Antibodies.
- Cu Elimination from Cu-Coordinating Macromolecules.
- Human norovirus inhibition by a human milk oligosaccharide.
- Human Norovirus GII.4(MI001) P Dimer Binds Fucosylated and Sialylated Carbohydrates
- Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization.
- Split-and-Combine Approach towards Branched Precision Glycomacromolecules and their Lectin Binding Behavior
- Epitope mapping of histo blood group antigens bound to norovirus VLPs using STD NMR experiments reveals fine details of molecular recognition.
- The bulky and the sweet: How neutralizing antibodies and glycan receptors compete for virus binding.
- Presenting Precision Glycomacromolecules on Gold Nanoparticles for Increased Lectin Binding
- Norovirus-like VP1 particles exhibit isolate dependent stability profiles.
- Atomic Structure of the Murine Norovirus Protruding Domain and Soluble CD300lf Receptor Complex
- Heteromultivalent Glycooligomers as Mimetics of Blood Group Antigens
- Norovirus assembly and stability
- Open Sesame: New Keys to Unlocking the Gate to Norovirus Infection
- Recent developments in solid phase strategies towards synthetic, sequence-defined macromolecules
- Fucose-Functionalized Precision Glycomacromolecules Targeting Human Norovirus Capsid Protein
- Spin ballet for sweet encounters. Saturation transfer difference NMR and X-ray crystallography complement each other in the elucidation of protein-glycan interactions
- Extracellular conformational changes in the capsid of human papillomaviruses contribute to asynchronous uptake into host cells
- Norovirus, glycans and attachment
- Sialic acids in non-enveloped virus infections
- Synthesis of highly controlled carbohydrate-polymer based hybrid structures by combining heparin fragments, sialic acid derivatives, and solid phase polymer synthesis
- Infectious Entry of Merkel Cell Polyomavirus
- Virus-like particle size and molecular weight/mass determination applying gas-phase electrophoresis (native nES GEMMA).
- A post-translational modification of human Norovirus capsid protein attenuates glycan binding.
- Structural mass spectrometry goes viral
- Divalent Sialylated Precision Glycooligomers Binding to Polyomaviruses and the Effect of Different Linkers
- The Symmetry of Viral Sialic Acid Binding Sites–Implications for Antiviral Strategies
- Structure of Merkel cell polyomavirus capsid and interaction with its glycosaminoglycan attachment receptor
- Structural Basis and Evolution of Glycan Receptor Specificities within the Polyomavirus Family.
- Glycan-induced protein dynamics in human norovirus P dimers depend on virus strain and deamidation status
- N-terminal VP1 Truncations Favor T = 1 Norovirus-Like Particles
- Protein Secondary Structure Affects Glycan Clustering in Native Mass Spectrometry
- Norovirus–glycan interactions — how strong are they really?
- Recovery, Purification, and Reusability of Building Blocks for Solid Phase Synthesis
- Prophylactic Antiviral Activity of Sulfated Glycomimetic Oligomers and Polymers
- Exploring Cyclic Sulfamidate Building Blocks for the Synthesis of Sequence‐Defined Macromolecules
- Synthesis and Self-assembly of Amphiphilic Precision Glycomacromolecules
- Progress, challenges and future directions of heterocycles as building blocks in iterative methodologies towards sequence-defined oligomers and polymers
- Glycans Controlling Virus Infections: Meeting Report on the 1st International Symposium on Glycovirology Schöntal, Germany, 02–04 May 2018
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